Profhilo: The New Biorevitalization Based on Pure Hyaluronic Acid

Profhilo is one of the most effective treatments to fight and eliminate skin laxity, but not only. Many compare it to a normal filler; in reality, it is a gel-based on hyaluronic acid that has a double action: rejuvenate and remodel.

Profhilo 逆時針 is a revolutionary treatment, a unique tool to the point of being awarded as the best aesthetic medicine product in 2016 and 2018. So let’s try to understand better how it works and what its peculiarities are for face and body skin.

How the treatment takes place:

Profhilo is injected into the BAP (BIO AESTHETIC POINTS) of the lower middle third of the face, an area particularly prone to laxity. In the 5 points per half face, 0.2 ml of profhilo are injected at the superficial subcutaneous level with a 29 G needle. This forms a bolus (swelling) of Profhilo, perceptible only to the touch, which will tend to dissolve in the following 48/72 hours as the hyaluronic acid spreads into the tissue.


The doctor outlines the entry points, taking into account the personal characteristics of the anatomy and the manifestation of age-related transformations. The skin is processed. The injection is made into the deep skin layers. Everything takes no more than 15-20 minutes.

After a month, the procedure must be repeated to consolidate the effect.

Advantages of the treatment

  • It stimulates the synthesis of type I, III, IV, VII collagen 
  • Stimulates the synthesis of elastin
  • Maintains and promotes the normal vitality of fibroblasts, keratinocytes, and adipocytes
  • Promotes remodeling of the extracellular matrix (in terms of elasticity and support)
  • It is more resistant to endogenous hyaluronidase (the enzyme that degrades hyaluronic acid). This allows the product to last longer, even though it is not cross-linked.
  • Few inoculation points 

Indications for treatment

  • Dull and asphyxiated skin
  • Dermal trophization
  • Skin laxity

How to behave after the treatment 

On the day of treatment with Profhilo, avoid massages, facial cleansing, radiofrequency treatments, and intense sport. Avoid taking aspirin, NSAID analgesics, and anticoagulants to reduce the risk of bruising. In the event of the onset of small hematomas, it is possible to mask them with the make-up recommended by the doctor. You can immediately resume your work and social habits.


  • Documented allergy to product components
  • Pregnancy 
  • Feeding time
  • Active infections in the treatment area (herpes simplex, active acne)
  • Hypertrophic scar diathesis or tendency to form keloids
  • Coagulopathies

When to perform the treatment

Any time of the year

Profile it before and after

Being a very safe treatment, Profhilo proves to be the ideal tool for all over 30s who wish to slow down the skin aging processes or hide their effects. The procedure is very simple: identify the area to be treated and proceed with the injection using very thin needles.

After the treatment, you can resume your daily life, but it would be better to avoid facial cleansing, radiofrequency treatments, massages, and sports training. In addition, it is not recommended to take aspirin, NSAID drugs, and anticoagulants to avoid the appearance of bruises.

The treatment gives fairly immediate effects from the first session, although to notice the “definitive” results, it would be better to undergo a cycle of 2 sessions 3 or 4 weeks apart. However, the results are temporary, lasting about 9 months, longer than with normal fillers.

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